Expression of H19 imprinted genes in the villus tissues of women with spontaneous abortion
- VernacularTitle:自然流产者绒毛组织中印记基因H19的表达及意义
- Author:
Xinyuan YANG
;
Wenli GOU
;
Yu WANG
- Publication Type:Journal Article
- Keywords:
spontaneous abortion;
imprinted genes;
H19
- From:Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of H19 imprinted genes in the villus tissues of women with spontaneous abortion.Methods Reverse transcription-polymerse chain reaction method(RT-PCR) was employed to detect H19 imprinted genes allele-specific expression levels of the villus tissues extracted from 45 cases of spontaneous abortion and 30 cases of normal pregnancy.Results Nineteen cases of 21 heterozygous cases in spontaneous abortion samples showed billelic expression of H19(19/21),whereas no billelic expression was found in the normal pregnancy samples(0/13)(P
