Correlation between gene HLA-class I polymorphism and susceptibility to leukemia
- VernacularTitle:HLA-I类基因多态性与白血病易感性的关联性研究
- Author:
Lanxia ZHOU
;
Li ZHAO
- Publication Type:Journal Article
- Keywords:
human leukocyte antigen(HLA);
leukemia;
PCR-SSO;
polymorphism
- From:Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between gene HLA-class I polymorphism and susceptibility to leukemia in Chinese Gansu Han people and search for the genes susceptible to leukemia.Methods HLA-A and B alleles polymorphism in 65 patients with leukemia and 48 normal subjects were determined by PCR with sequence specific oligucleotide probe(PCR-SSO).Results The allele frequencies of HLA-A01 and B38 were increased (P
