Immunoregulatory Effects of ?-3 Polyunsaturated Fatty Acid and Its Applications in Organ Transplantation
- VernacularTitle:?-3多不饱和脂肪酸的免疫调节作用及其在器官移植中的应用
- Author:
Ming ZHANG
;
Bo LI
- Publication Type:Journal Article
- Keywords:
?-3 fatty acid Immunoregulation Organ transplantation
- From:
Chinese Journal of Bases and Clinics in General Surgery
2003;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the immunoregulatory effects of immunonutrient ?-3 polyunsaturated fatty acid (PUFA) and its applications in organ transplantation. Methods Relevant literatures of recent years were reviewed. Results The immunoregulatory effects of ?-3 PUFA can inhibit proliferation and activation of the immunocompetent cells including T cell and B cell, reduce cytokine production, modulate immunologic response, improve graft function, pro-long survival, reduce episodes of rejection, and lessen adverse reactions of immunosuppressor.Conclusion ?-3 PUFA should have wide applications in organ transplantation due to its immunoregulatory effects. However, this research should be further studied.
