Application of Magnetic Resonance Spectroscopy in Diagnosis of Intracranial Lesions
- VernacularTitle:MRS在脑内占位病变诊断中的应用
- Author:
Hong YIN
;
Jian ZHANG
;
Yuangui GAO
;
Lin MA
- Publication Type:Journal Article
- Keywords:
brain;
MR spectroscopy;
neoplasm
- From:
Journal of Practical Radiology
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical value of MR spectroscopy in intracranial neoplasm. Methods 52 cases with brain neoplasm or recurrent neoplasm or non-tumor lesion confirmed by pathology were undergone proton MRS before stereotactic biopsy, or operation. Results Of 52 cases, 38 were neoplasm and 14 were nonneoplastic lesion, 34 of 38 brain tumor, 11 of 14 nonneoplastic lesion were diagnosed correctly. The characteristics on MRS of glioma were remarkable Cho increase and NAA decrease, Lac in the tumors and the central necrotic area was elevated. Metastasis: Cho increased,NAA disappeared or obviously decreased and Lac increased, but the peritumoral region was normal. Lymphoma: Cho increased, NAA decreased moderately, Lip presented, but the peritumoral region was normal. Demyelination lesion: slight or median decreased NAA and normal Cr, Lac increased slightly. All metabolism decreased or disappeared in radiation necrosis, Cho was relative high compared with NAA. Brain abscess: Lac increased in the centre of abscess and perilesion was normal.Conclusion MRS has significant value in detecting and differentiating brain lesions.
