Expressions of cyclooxygenase-2 and epidermal growth factor receptor in non-small cell lung cancer
- VernacularTitle:环氧化酶-2及表皮生长因子受体在非小细胞肺癌组织中的表达及临床意义
- Author:
Xilin DONG
;
Yong ZHANG
;
Ming XIE
- Publication Type:Journal Article
- Keywords:
cyclooxygenase;
epidermal growth factor receptor;
non-small cell lung cancer
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expressions of cyclooxygenase-2(COX-2) and epidermal growth factor receptor(EGFR) in tumor tissues and explore the effect of COX-2 and EGFR in NSCLC development.Methods The expression of COX-2 and EGFR was detected by immunohistochemical technique in 56 cases of non-small cell lung cancer(NSCLC) and in 20 cases of normal lung tissues.Results The expression of COX-2 and EGFR in NSCLC was significantly higher than that in normal lung tissues(P
