Inactivated bone replantation with preservation of the epiphysis for osteosarcoma in children
- VernacularTitle:保留骨骺灭活再植术治疗儿童股骨远端骨肉瘤
- Author:
Xiuchun YU
;
Xiaoping LIU
;
Yin ZHOU
- Publication Type:Journal Article
- Keywords:
osteosarcoma with inactivated bone replantation;
epiphysis;
complication
- From:
Orthopedic Journal of China
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To study the clinical matters of inactivated bone replantation with preservation of the epiphysis in children limb salvage with osteosarcoma.[Method]Eleven children(mean age 7.6 years old,5 male and 6 female)with osteosarcoma underwent inactivated bone replantation with preserving epiphysis following chemotherapy during 6 years.All lesions located in the distal femur.Seven were in Ⅰ type on MRI classification,4 in Ⅱ type.Two courses of the same protocol as preoperative chemotherapy were administered postoperatively.[Result]The operative time were 3~4 hours.The bleeding amount were about 300~500 ml.No complications occurred in operation and incisions healed well in all patients.Eleven patients were done follow-up from 10 to 72 months.Functions of the affected limbs were satisfatory.Local tumor recurrence was seen in one case and lung metastasis in two,3 patients died of the disease.Blot became flexible and inactivated bone fractured in one,respectively.[Conclusion]Inactivated bone replantation with preserving epiphysis for osteosarcoma in children is propitious to recover limb function and keep limb length.The main measures of preventing complications include no-touch technique in operation,incision drain completely,prolonging time of affected limb external fixation and safeguarding the affected limb during postoperative function exercise.
