Steroid Receptor Coactivator Family and Breast Cancer
- VernacularTitle:类固醇受体辅活化因子家族与乳腺癌
- Author:
Peng TANG
;
Jun JIANG
- Publication Type:Journal Article
- Keywords:
Steroid receptor coactivator Breast cancer Steroid hormone Steroid receptor
- From:
Chinese Journal of Bases and Clinics in General Surgery
2003;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of steroid receptor coactivator family in initiation, development, treatment and prognosis of breast cancer. Methods The literatures in recent years which have related to the effect of steroid receptor coactivators in breast cancer are reviewed. Results Steroid receptor coactivators are essential for several kinds of steroid hormones binding to steroid receptors, so they are important accessory factors that induce the initiation, development and recurrence of breast cancer, and predictive factors that estimate the prognosis of breast cancer. Conclusion Inhibition of the expression and signaling pathway of steroid receptor coactivators may be effective for breast cancer prevention and treatment.
