CD4~+CD25~+/CD4~+CD25~(high) regulatory cells in peripheral blood of cancer patients
- VernacularTitle:恶性肿瘤患者CD4~+CD25~+/CD4~+CD25~(high)调节性T细胞的研究
- Author:
Junxia YAO
;
Li LIU
;
Shiang HUANG
- Publication Type:Journal Article
- Keywords:
Malignancy;
CD4+CD25+ regulatory T cells;
Flow cytometry
- From:
Chinese Journal of Immunology
1985;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the frequencies of CD4+ regulatory T(Treg) cells(CD4+CD25+/CD4+CD25high) in peripheral blood of cancer patients,providing the opportunity to determine whether cancer patients exhibit an expanded CD4+CD25high pool. Methods: The frequency of CD4+CD25+/CD4+CD25high Treg in the peripheral blood of 62 cancer patients and 15 controls was determined by flow cytometry. Results: Compared with those of healthy control, the frequency of CD4+CD25+/CD4+CD25high in the peripheral blood of cancer patients showed a significant increase[(19.61?8.17)%/(4.20?1.90)%,P
