Effects of 900 MHz Electromagnetic Field on DNA and the Protein Expression of p53 Gene in Human Embryonic Lung Cells
- VernacularTitle:900MHz电磁辐射对人胚肺细胞DNA及p53基因蛋白表达的影响
- Author:
Jun FANG
;
Xianggang HUANG
;
Ling MA
- Publication Type:Journal Article
- Keywords:
Radiation;
DNA damage;
p53 gene
- From:
Journal of Environment and Health
1992;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of 900 MHz electromagnetic field(EMF)on DNA and the protein expression of p53 gene in human embryonic lung cells.Methods Single cell gel electrophoresis(SCGE)and Western Blot were used for the research.Results The results showed that 900 MHz EMF could not damage the DNA of human embryonic lung cells when the exposure time was 1 h and the exposure doses were 1,2,5 and 8 mW/cm2 respectively;900 MHz EMF could not affect the protein expression of p53 gene in human embryonic lung cells when the exposure time was 12 h and the exposure doses were 1,2,5 and 8 mW/cm2 respectively.Conclusion At the exposure doses in the present research,900 MHz EMF neither can damage the DNA of cells,nor can affect the protein expression of p53 gene,so the results can not sustain the issue that 900 MHz EMF may cause cancer.
