Effects of extracellular ATP on the recovery of motor function after spinal cord injury in rats
- VernacularTitle:细胞外ATP对大鼠脊髓损伤后运动功能恢复的影响
- Author:
Jun QIAN
;
Yanchao MA
;
Yayi XIA
;
Hua HAN
;
Zhengyi SUN
- Publication Type:Journal Article
- Keywords:
spinal cord injury;
adenosine triphosphate;
motor function;
rat
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of extracellular ATP on the recovery of motor function after spinal cord injury in rats.Methods Twenty healthy adult rats were randomly divided into two groups after contusion injury was performed by the weight drop method at T10 with Allen impactor.Group A(ATP group) and group B(control group) each had ten rats.At days 1,3,7,14 and 28 after injury,the recovery of motor function after spinal cord injury in rats was assessed with modified Tarlov scores and slanting board test.Results Modified Tarlov scores and slanting board test were better in group A than in group B after spinal cord injury in rats.Significant difference was found in modified Tarlov scores and slanting board test between the two groups at days 14 and 28 after injury(P
