Antagonism of DMSO against Genotoxicity of Cooking Oil Fume Condensate to BEAS-2B Cell
- VernacularTitle:二甲基亚砜拮抗烹调油烟冷凝物遗传毒性的研究
- Author:
Bo HUANG
;
Feng CHEN
;
Maoxiang ZHU
- Publication Type:Journal Article
- Keywords:
Air pollution,indoor;
Cooking oil fumes condensation;
Genotoxicity;
BEAS-2B cell;
DMSO
- From:
Journal of Environment and Health
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the antagonism of DMSO against the toxicity of cooking oil fume condensation to BEAS-2B cell.Methods The comet assay,micronucleus test and multinucleated cells test were used to research the genotoxicity induced by cooking oil fume condensation(COFC)and the antagonism of DMSO.Results COFC induced DNA broken,the tail area,rate of comet occurrence,tail length,tail moment,olive tailmoment increased significantly,the frequencies of micronucleus and multinucleated cells were significantly increased and the damage of cells could be inhibited effectively by DMSO.Conclusion The antagonistic effects of DMSO on the toxicity of COFC was significant in BEAS-2B cell.
