The correlation between expression of focal adhesion kinase and vascular endothelial growth factor in human rectal carcinoma
- VernacularTitle:FAK和VEGF在直肠癌中的表达及其相互关系的研究
- Author:
Jingyuan WANG
;
Jianliang ZHANG
- Publication Type:Journal Article
- Keywords:
Rectal neoplasms?Focal adhesion kinase?Vsacular endothelial growth factor
- From:
Chinese Journal of Current Advances in General Surgery
1998;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To detect the expression of focal adhesion kinase (FAK) and vascular endothelial growth factor (VEGF) in human rectal carcinoma, to study their correlation in invasion and metastasis. Methods: The expression of FAK and VEGF in 86 specimens resected from patients with rectal carcinoma and 30 non-rectal carcinoma specimens, was investigated by immunohistochemical SABC method respectively. Results: the positive rate of FAK, VEGF was 80 % and 59% respectively in rectal carcinoma. However, non-rectal carcinoma was 10% and 13 % respectively. The diference was significant (P
