Effect of Ginsenosides on Learning,Memory and Activity of Rats During Sleep Deprivation
- VernacularTitle:人参皂甙对睡眠剥夺大鼠学习记忆和活动性的影响
- Author:
Guoyu YANG
;
En HUANGFU
;
Dajun ZHANG
;
Zhengzhi FENG
- Publication Type:Journal Article
- Keywords:
Sleep deprivation;
Ginsenosides;
Rat;
Learning;
Memory;
Activity
- From:Chinese Journal of Clinical Psychology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the effects of ginsenosides(GS) on learning,memory and activity of rats during sleep deprivation(SD).Methods: SD was induced in Sprague-Dawlay rats by employing "flower pot" technique.The rats were randomly divided into five groups according to the time of SD(0-96h),and every group was also divided into two subgroups: experimental group(E) and control group(C).Forced feeding of GS to the experimental rats for 5 d before the rats were deprived of sleep.Before and after SD immediately,the behaviors of rats were studied in "Y" maze test,step-down test and open-field test.Results: ①"Y" maze test: As compared with those of the controls,the accuracy of response of experimental groups increased significantly in 24h,48h,72h and 96h(P
