Association of MICA-STR with leukemia in Hunan Han population
- VernacularTitle:湖南地区白血病MHC-Ⅰ类链相关基因A微卫星多态性分析
- Author:
Lixin LI
;
Wei TIAN
;
Qizhi LUO
;
Fan WANG
- Publication Type:Journal Article
- Keywords:
Leukemia;
MHC class-Ⅰ chain related gene A;
Microsatellite allele;
Association
- From:
Chinese Journal of Immunology
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).Subsequent stratification revealed that MICA*A5 was present at significantly lower frequency in patient group with chronic granulocytic leukemia(CML)(RR=0.635,P=0.038 0);MICA*A4 at significantly lower frequency in patient group with lyphololastic leukemia(ALL)(RR=0.120,P=0.029 7);MICA*A5 at significantly higher frequency in patient group with acute non-lyphololastic leukemia(ANLL)(RR=2.229,P=0.021 8),all compared with control group.Conclusion:MICA-STR allelic variation is associated with leukemia in Hunan Han population;The data also suggest the heterogeneity of MICA-STR allele associated with different clinical types of leukemia.
