Expression of CD137 in the peripheral blood T lymphocytes from patients with systemic lupus erythematosus
- VernacularTitle:系统性红斑狼疮患者CD4~+ T细胞上CD137的表达
- Author:
Rong ZHANG
;
Xiaoguang LUO
;
Xiaoli ZHANG
;
Lijuan ZHAO
- Publication Type:Journal Article
- Keywords:
Systemic lupus erythematosus;
T lymphocytes;
CD137
- From:
Chinese Journal of Immunology
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the expression and role of costimulatory molecule CD137 on CD4+T cell in patients with systemic lupus erythematosus(SLE).Methods:The expression of CD137 on T lymphocyte from 30 SLE patients and 20 healthy controls were detected by flow cytometry.Results:The expression of CD137 on CD4+T lymphocytes from patients with active SLE were significantly higher than that of patients with inactive SLE and normal control(21.56?4.08 vs 3.01?0.09,1.24?0.12,P
