Expression of Survivin in Human osteosarcoma and its correlation with PTEN and cyclinD1
- VernacularTitle:凋亡抑制蛋白Survivin在骨肉瘤中的表达及其与PTEN、cyclinD1蛋白表达的关系
- Author:
Guoqing DUAN
;
Shuzhong LI
- Publication Type:Journal Article
- Keywords:
osteosarcoma;
Survivin;
PTEN,cyclinD1;
immunohistochemistry
- From:
Orthopedic Journal of China
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To investigate the expression of Survivin and its relationship with expression of PTEN and cyclinD1.[Method]Immonohistochemical method(SP method)was used to detect the expression of Survivin,PTEN and cyclinDl in 40 osteosarcoma tissues and 20 ostanchondroma tissues.[Result]The expression rate of Survivin was significantly higher in osteosarcoma(62.5%)than that in osteochondroma(10.0%)(P
