Progress in effects of the HGF/SF-c-Met on progression of tumors and inhibitors of its pathway
- VernacularTitle:HGF/SF-c-Met通路在肿瘤进展过程中的作用及其阻断的研究进展
- Author:
Yuexin LING
;
Tao SUO
;
Saixiong TONG
- Publication Type:Journal Article
- Keywords:
HGF/SF-c-Met pathway;
tumor;
inhibitor
- From:
China Oncology
1998;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Over-expression of the HGF/SF-c-Met plays an important role in tumor metastasis. It has been demonstrated that activation of its pathway may promote almost every step of tumor metastasis. Recently, blocking its pathway to prevent tumor cell metastasis has become a focus in anti-tumor studies. This review will address the progress in studies on the effects of HGF/SF-c-Met on growth, invasion, and metastasis of tumors and inhibitors of its pathway.