Effect of Candida albicans on cell cycle distribution of KB cells
- VernacularTitle:白色念珠菌对口腔上皮细胞细胞周期的影响
- Author:
Ling ZHANG
;
Xiaolin TANG
;
Zhaoyuan WANG
- Publication Type:Journal Article
- Keywords:
Candida albicans;
Cells cycle;
Oral epithelial cells
- From:
Journal of Practical Stomatology
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of Candida albicans(C. albicans) on the cell cycle distribution of oral epithelial KB cells in vitro. Methods:KB cells at 3?106/ml were seeded and cultured for 48 h, then the bacterial filament and the spore of C. albicans at 102 CFU/ml were added to the cultures respectively. KB cell culture without C. albicans was used as the control. After 48 h culture cell suspensions were prepared and subjected to FACS flow cytometry for detecting the cell cycle distribution. Results:Filament of C. albicans decreased the percentage of G0/G1 cells, increased G2/M cell population and proliferation index of the cells(P
