Establishment of orthotopic simultaneous liver-kidney transplantation model in the rats
- VernacularTitle:大鼠原位肝肾联合移植模型的建立
- Author:
Xuyong SUN
;
Lixin YU
;
Xiaoyou LIU
;
Qian YUAN
- Publication Type:Journal Article
- Keywords:
Rats;
Simultaneousis liver-kidney transplantation;
Model;
Animal
- From:
Chinese Journal of Urology
2006;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a simple,reliable and high successful model of simultaneous liver-kidney transplantation(SLKT). Methods SLKT were performed with some self-made instruments in healthy male SD rats as the recipients,and other SD rats as the donors.The donor liver and kidney were resected simultaneously.The anastomosis of inferior vein cava(IVC) and kidney artery was modified. Results The operation time of donors was (38?5) min;no liver period of recipients was (20?3) min,the operation time of recipients was (81?13)min,the hot ischemic time was less than 4 s,cold ischemic time was less than 83 min,the successful rate is 87.1%(183/210) and postoperation complication was 12.9%(27/210). Conclusions The new model of simultaneous liver-kidney transplantation in the rat was simple,high successful,easily repeated and the complications rate was low.It might be a good model of fundamental research on simultaneous liver-kidney transplantation in the rat.
