Effects of alpha-1-adrenergic receptor subtype-selective antagonists on lower urinary tract function in rats with bladder outlet obstruction
- VernacularTitle:?-1AR亚型拮抗剂对膀胱出口梗阻大鼠排尿的影响
- Author:
Baojun GU
;
Feng LIU
;
Yuemin XU
- Publication Type:Journal Article
- Keywords:
Bladder outlet obstruction;
Rat;
Alpha-1 adrenergic receptors;
Micturition
- From:
Chinese Journal of Urology
2006;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
500 mg,frequency was reduced in rats treated with tamsulosin (P500 mg,and the combined ?1a/?1dAR antagonist tamsulosin reduces urinary frequency more than the ?1aAR selective antagonist 5MU.This finding supports the hypothesis that the ?1dAR is important in mediating irritative symptoms.
