Study of senile escaping phenomenon in prostatic tissues
- VernacularTitle:前列腺衰老逃逸现象的实验研究
- Author:
Tiejun PAN
;
Xiangbao MENG
;
Zhangqun YE
- Publication Type:Journal Article
- Keywords:
Benign prostatic hyperplasia;
Telomerase;
Senile escaping
- From:
Chinese Journal of Urology
2006;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the mechanism of senile escaping of benign prostatic hyperplasia(BPH) condition. Methods With polymerase chain reaction based telomeric repeat amplification protocol assay(TRAP),telomerase activity was examined in 13 normal prostate tissues,35 benign prostatic hyperplasia tissues,33 hyperplastic tubercle and diaphragm. Results Telomerase activity was detected in 2 of 13(15%)normal prostate tissues,17 of 35(49%)benign hyperplasia tissues,14 of 33(42%)hyperplastic tubercle tissues and 1 of 33(3%)diaphragm tissues.The positive rate of telomerase in BPH is higher than normal prostate (P
