The effect of rhGH on the apoptosis and expression of P53 in IgA plasmocytes of intestinal wall after intestinal ischemia-reperfusion injury of rats
- VernacularTitle:重组人生长激素对肠缺血再灌注大鼠肠壁IgA浆细胞凋亡及P53基因表达影响的实验研究
- Author:
Haibo LIU
;
Shaochuan SUN
;
Chunning ZHENG
;
Yongsheng JIANG
- Publication Type:Journal Article
- Keywords:
Somatotropins,recombinant?Intestines?Reperfusion injury?ImmunoglobulinA?plasma cells?Genes,P53 Rats,Wistar
- From:
Chinese Journal of Current Advances in General Surgery
2004;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effect of rhGH on apoptosis and the expression of P53 of IgA plasmocytes of intestinal wall after intestinal ischemia-reperfusion injury and the correlation between apoptosis and the expression of P53.Methods:60 Wistar rats were divided into two groups randomly:experiment group(1.33U/kg rhGH was given q.d) and control group.Each group was divided into 3 subgroups(2,4,6days,respectively).Apoptosis and the expression of P53 in IgA plasmocytes of ileal mucosal were observed.[WTH7X]Results:[WT5”XY](1)Apoptosis of IgA plasmocytes in experiment group was lower than that in control group on 2~ nd ,4~ th ,6~ th day and had statistical significance(P
