The diagnostic value of plasma D-dimer as an early marker in acute mesenteric Ischemia
- VernacularTitle:D-二聚体在早期诊断急性肠系膜缺血的价值
- Author:
Xiangmin DING
;
Linhai ZHU
;
Xicheng ZHANG
- Publication Type:Journal Article
- Keywords:
D-dimer?Mesenteric artery,superior ?Ischemia
- From:
Chinese Journal of Current Advances in General Surgery
2004;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:In this study we evaluated the diagnostic value of plasma D-dimer level as an early indicator in acute mesenteric ischemia in rats.Methods:Forty-eight mature male Wistar rats were divided equally into experimental group (EG) and control group (CG),The superior mesenteric artery was ligated In EG,and while a simple laparotomy was performed in CG.Blood samples were taken for laboratory test in both groups at 1h、6h、12h respectively.Results:The longer the duration of mesenteric ischemia,the higher were the serum D-dimer levels in the study groups,and statistical significance was obtained between these two groups (P=0.0375).Otherwise,significant difference was not found in other laboratory parameters between them.Conclusions:Serum D-dimer dynamic measurements may be a important valuable screening parameter in the early diagnosis of mesenteric ischemia.