The expression of vascular endothelial cell growth factor and the microvessel density and their relationship with pathological types and clinical stages of gastric carcinoma
- VernacularTitle:肿瘤微血管密度和血管内皮生长因子的表达与胃癌病理及临床分期的关系
- Author:
Fenrong WANG
;
Rong LI
;
Zhengjun SONG
- Publication Type:Journal Article
- Keywords:
gastric cancer;
microvessel density;
vascular endothelial growth factor;
Borrmann type;
TNM stage
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship of the microvessel density(MVD) and the expression of vascular endothelial cell growth factor(VEGF) with the pathological types and clinical stages of gastric cancers.Methods The MVD and expression of VEGF in 45 patients with gastric cancer were assayed by using SP immunohistochemical method.The relationship of the MVD and VEGF with the pathological TNM types and clinical stages of gastric cancer was analyzed.Results In the marginal area where the gastric cancer grew actively,the microvessel density(MVD) was the highest;the expression of vascular endothelial cell growth factor(VEGF) in the cancerous cell plasm was significantly higher than that in the neighboring noncancer tissues(P
