Study on the relationship between female Alzheimer's disease and the level of estrogen
- VernacularTitle:女性阿尔茨海默病与雌激素水平的关系
- Author:
Hua YANG
;
Qiumin QU
;
Jianfeng HAN
;
Chengbin WU
- Publication Type:Journal Article
- Keywords:
Alzheimer's disease;
dementia;
sex hormone;
estrogen;
female
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyse the levels of estrogen in women patients with Alzheimer's disease(AD),and the relationship of estrogen level,menarche age,age of menopause,pregnancy times with severity of AD.Methods A 1:1 matched case-control study was conducted.The study subjects were given neuropsychological test face to face in questionnaire,including MMSE,ADL,POD,FOM,WISE and HMT depression scale.All the women subjects accepted another questionnaire concerning menarche age,age of menopause and pregnancy times.Radioimmunoassay was used to measure the sex hormone level of all the subjects.Results The level of estrogen in serum was obviously lower in AD group than in the control group(P
