Clinical Application of Collagenase Chemonucleolysis in Treatment of Cervical Disc Herniation
- VernacularTitle:胶原酶溶解术治疗颈椎间盘突出症的临床应用
- Author:
Yiqing WANG
;
Dawei ZHU
;
Fengqi REN
;
Ying REN
;
Fanjun XIA
- Publication Type:Journal Article
- Keywords:
cervical spine;
disc herniation;
collagenase;
chemonucleolysis
- From:
Journal of Practical Radiology
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To introduce the method and to evaluate the therapeutic effect of collagenase chemonucleolysis for treatment of cervical disc herniation.Methods 92 patients with cervical herniated discs were selected from January 2002 to December 2004.The procedure was guided by DSA and the puncture was defined from C_(6~7) or C_7-T_1 extradural cavity.Collagenase(1200~2400 u) was injcted in the herniated extradural cavity through the micrcatheter.Results The procedure of 88 cases was successful.80 cases were followed up from 6 to 12 months.The effect showed that 70 cases(87.5%) were excellent or good.No serious complication occurred.Conclusion The method of collagenase chemonucleolysis for treating cervical disc herniation is safe and effective,it can be used in clinic.