The effects of compressive stress on TGF-?1 expression in condylar cartilage in vitro
- VernacularTitle:静压力对髁突软骨转化生长因子?1表达影响的体外研究
- Author:
Zhang MIN
;
Li SONG
;
Xu YUN
- Publication Type:Journal Article
- Keywords:
Mandibular condylar;
Cartilage;
Organ culture;
Compressive stress;
Transforming growth factor -?1
- From:
Journal of Practical Stomatology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the expression of transforming growth factor-?1 (TGF-?1) in mandibular condylar chondrocytes after the condylar cartilage was stimulated by compressive stress.Methods:20 condylar cartilage samples were obtained from 10 new borne SD rats and cultured for 24 h.Then,10 samples were treated by a static compressive stress with a magnitude of 10 kPa for 1 h.Another 10 samples without stress treatment were used as the controls. At end of stress stimulation, the expression of TGF-?1 in the samples of both groups was examined by immunohistochemistry and image pattern analysis.Results:The grayscale values of TGF-?1 in perichondrium lay of stress treated and control samples were 159.21?19.84 and 174.20?14.47(P
