Effects of teletherapy and located hyperthermia on VX_2 rabbits'cytokines
- VernacularTitle:外照射与局部热疗对荷VX_2瘤兔细胞因子的影响
- Author:
Jianguo LIU
;
Qiuju HAN
;
Jiwei YU
- Publication Type:Journal Article
- Keywords:
Teletherapy;
Located hyperthermia;
VX_2 rabbits;
Cytokines
- From:
Cancer Research and Clinic
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe teletherapy and local hyperthermia effects on VX2 carcinoma rabbits'cytokines and curative effect. Methods 60 male white health rabbits were selected, and divided them into three group. The group of teletherapy were 20. The group of local hyperthermia were 20. So were the group of comparison. Their tumors' changes, rates of death and changes of IL-2, IL-6, IL-8, TNF, IGF, CA-50 before and after VX2 carcinoma replanted and those treated after one, three, four weeks were observed. Results The diameters of tumors and rates of death from large to small in turn was comparison's group, hyperthermia's group and teletherapy's group. After VX2 carcinoma replanted IL-2, IL-8 were low but IL-6, TNF, IGF, CA-50 were high. After being treated one, three or four weeks, IL-2, IL-8 were getting lower and lower but there was significant difference between teletherapy's group with other group in IL-2 and IL-8(P
