Level and Significance of Inflammatory Cytokines in Patients with Acute Deep Venous Thrombosis of Lower Extremity
- VernacularTitle:急性下肢深静脉血栓形成患者IL-6、IL-8、IL-10及TNF-?的水平及意义探讨
- Author:
Xiangyu ZHOU
;
Yanzheng HE
;
Chunshui HE
;
Yong LIU
- Publication Type:Journal Article
- Keywords:
Lower extremity deep venous thrombosis Cytokine Inflammation
- From:
Chinese Journal of Bases and Clinics in General Surgery
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
To study the significance of the levels of plasma inflammatory cytokines (IL-6,IL-8,IL-10 and TNF-?) in patients with acute deep venous thrombosis (DVT) of lower extremity. Methods Forty untreated DVT cases were selected as the subjects in the DVT group, while thirty healthy subjects, whose ages and genders showed no significant difference with the DVT patients, were collected as the control group. The plasma levels of IL-6, IL-8 and TNF-? were detected by radioimmunoassay (RIA), and the plasma level of IL-10 was measured by enzyme-linked immunosorbent assay (ELISA). Correlation analysis was used to investigate the relationships between the levels of different inflammatory cytokines within DVT group. Results The levels of plasma cytokines in the DVT group were all significantly higher than those in control group (P
