Restorative effects of Radix Notoginseng on hepatic lesions provoked by CCl4 in experimental mice
- Author:
Duong Thi Ly Huong
- Publication Type:Journal Article
- Keywords:
Hepatic
- MeSH:
Animal Experimentation;
Mice;
Liver
- From:Pharmaceutical Journal
2004;44(2):38-41
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Restorative effects of Radix Notoginseng on liver damage provoked by CCl4 in experimental rats. Results showed that an oral adminitration of Radix Notoginseng (RN) 5g/kg of body weight exerted moderate effect of recovering on CCl4 induced liver damage in rats. Although the serum ASAT enzym/concentration in CCl4 – intoxicated and RN treated group was still higher than that of control group after 1 day, it was significantly lower than that of intoxicated and non treated group (p<0,01). There were no difference in ALAT concentration between these 2 groups. 4day course of treatment by RN has reduced both ASAT and ALAT serum levels to normal levels while ASAT level in CCl4 intoxicated rats was still higher
