Study on Micronuclei and Nuclear Abnormalities Induced by Cu~(2+) in Hemiculter leucisculus Erythrocytes
- VernacularTitle:铜离子诱发■鲦鱼红细胞微核及核异常的研究
- Author:
Guisheng ZHANG
;
Daoyu ZHU
- Publication Type:Journal Article
- Keywords:
Metal, heavy;
Copper;
Erythrocytes;
Micronucleus test;
H.leucisculus
- From:
Journal of Environment and Health
1989;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective The genetic toxicity of copper was studied in Hemiculter leucisculus erythrocytes to find the sensitive fishes for mutagens. Methods Cu2+ was used as the mutagen and H. leucisculus as the testee. 120 H. leucisculus were randomly divided into 8 groups, treated with Cu2+ at the concentration of 0.01, 0.02, 0.04, 0.08, 0.16, 0.32, 0.64 and 1.28 mg/L respectively. Results Compared with the control, the frequency of micronuclei and nuclear abnormalities of erythrocytes in the Cu2+ treated groups significantly increased (P
