Effect of vitamin K3 decreasing the urine oxalate excretion in rats
- VernacularTitle:维生素K_3降低诱石模型大鼠尿草酸排泄的量效关系研究
- Author:
Shiqing ZHANG
;
Guohai SHI
;
Wenfeng LI
- Publication Type:Journal Article
- Keywords:
Oxalates;
Vitamin K3;
Rats;
Kidney calculi
- From:
Chinese Journal of Urology
2006;0(S2):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of vitamin K3 decreasing the urine oxalate excretion in rats. Methods A total of 80 male Sprague-Dawley rats (body weight, 200-250g) were randomly divided into 8 groups, ie, control group, only vitamin K3 group, stone forming group, stone forming plus 4.0、3.0、2.0、0.8、0.4mg/d Vit K3 group. Each group is 10 rats respectively. The change of urine oxalate was observed. Results Vitamin K3 can reduce the 24h urine oxalate excretion in stone-forming group rats, but there were no effects in control group rats(P
