Research on the ADAM gene expression in patient with infertility
- VernacularTitle:男性不育症患者精液ADAM基因表达的临床意义
- Author:
Chunyin YAN
;
Jianping ZHUANG
;
Jianquan HOU
;
Jinxian PU
;
Jinxing LV
;
Duangai WEN
- Publication Type:Journal Article
- Keywords:
Infertility;
ADAM gene;
mRNA expression
- From:
Chinese Journal of Urology
2006;0(S2):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the ADAM gene expression and unknown reason infertile patients. Methods With RT-PCR mehtod, we checked from normal group semen 30 cases and infertile group semen 30 cases in order to know the ADAM1,2,3,32 mRNA expression. Results there are the ADAM1,2,3,32 gene expression in all 30 cases of normal group whereas in 30 cases infertile patients there exists 1 case ADAM1,2,32 lacking expression, 1 case ADAM2,32 lacking expression, 1 case ADAM1 and 1 case ADAM3 lacking expression. Conclusions The lacking of ADAM1,2,3,32 may be one of the most reasons which cause the infertility.
