Experimental studay on bridging the femoral defects with differently-treated allograft of cortical plates
- VernacularTitle:不同异体皮质骨板桥接股骨缺损的实验研究
- Author:
Hongwu PAN
;
Shigui YAN
- Publication Type:Journal Article
- Keywords:
allograft;
bridging;
femur;
defect;
biomechnics
- From:
Orthopedic Journal of China
2006;0(21):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To observe the effect of bridging rabbit femoral bone defect by allograft of cortical plates.[Method]Allograft of cortical plates of frozen bone group,alcohol group and fresh group were transplated randomly into rabbit femoral bone defecs.The rabbit femoral bone defects were harvested in the 4~(th),8~(th) and 12~(th) week after the tansplantation and the biological process of allograft of cortical plates in the rabbit were analysed biomechanically,radiologically and histologically.[Result]The flexion stress and translation of the frozen group,alcohol group and fresh group were almost equal in the 4~(th) week after transplantation and there were big difference between the former two groups and fresh group.From the X-ray allograft of cortical plates were fused with host bone in the alcohol group and no fusion in the fresh group.In the 4~(th) week osteocytes were found in the frozen group and alcohol group and no in the fresh group.In the 8~(th) week the consecutive array of osteocytes were found in the frozen group and alcohol group and a little in the fresh group.In the 12~(th) week lots of consecutive array of osteocytes were found in the frozen group and alcohol group than that in the fresh group.[Conclusion]The frozen and alcohol treated and fresh allograft of cortical plates have initial biomechanical support.The allograft of cortical bone frozed group and alcohol group can fuse with host bone and that of fresh group have less ability to fuse with host bone due to immunological rejection.
