The effect of Lifein combined with cisplatin on malignant ascites and telomerase activity
- VernacularTitle:力尔凡联合顺铂对恶性腹腔积液临床疗效及端粒酶活性的影响
- Author:
Jingyuan CUI
;
Hong MA
;
Qiujuan CUI
;
Dongfeng ZHOU
- Publication Type:Journal Article
- Keywords:
Lifein?Cisplatin?Ascites?Telomerase
- From:
Chinese Journal of Current Advances in General Surgery
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the clinical value and telomerase activity of malignant ascites treated by lifein combination with cisplatin.Methods:48 patients with malignant ascites were divided randomly into two groups.Treatment group of 28 cases were treated with lifein and cisplatin,control group of 20 cases were treated with cisplatin alone.Telomerase activity was detected by semi-TRAP assay before treatment,at the first week,the second week and the third week after treatment,respectively.Results:the effective rates of treatment group(89.3%) was much higher than that of control group (60%),P