Effects of Matrine on proliferation and apoptosis of Hela cells in vitro
- VernacularTitle:苦参素对Hela细胞增殖及凋亡的影响
- Author:
Mu LI
;
Baoshan SU
;
Zongfang LI
;
Jun YANG
;
Wei TIAN
;
Lingxia ZENG
- Publication Type:Journal Article
- Keywords:
matrine;
hela cells;
proliferation;
apoptosis
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of Matrine on proliferation and apoptosis of human cervical carcinoma cell line Hela in vitro. Methods Human cervical carcinoma cell line Hela was cultured in vitro. Cell proliferation was assessed by MTT colorimetric assay. The percent age of apoptosis cells was detected by TUNEL staining. The expression of PCNA protein was displayed with immunohistochemistry. Results Proliferation of Hela cells was inhibited in 0.5, 1.0, 1.5, 2.0, 2.5, and 3.0g/L Matrine-treated groups compared with those in the control group(P
