Present status on the research of genetics of familial clear renal cell carcinoma
- VernacularTitle:家族性肾透明细胞癌的遗传学研究现状
- Author:
Jianzhong SHOU
;
Jianhui MA
- Publication Type:Journal Article
- Keywords:
Genetics;
Familial clear renal cell carcinoma
- From:
Cancer Research and Clinic
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Familial clear renal cell carcinoma consists of hereditary clear renal cell carcinoma syndromes and familial non-syndromic renal cell carcinoma,of which the former can be the renal cell carcinoma accompanied with von Hippel-Lindau disease(VHL), Tuberous Sclerosis Complex(TSC), Birt-Hogg-Dube(BHD) syndrome and familial translocation of chromosomal 3. The most commonly involved gene includes VHL, TSC and BHD. Here, the current research status of familial clear renal cell carcinoma is reviewed.