Effects of desflurane on cardiac troponin Ⅰ and myocardial enzyme in patients with thoracic cancer
- VernacularTitle:地氟醚对胸部肿瘤患者心肌酶和心肌肌钙蛋白I的影响
- Author:
Lianbing GU
;
Shuliang MA
;
Fenglun HUANG
;
Zhichao LIANG
- Publication Type:Journal Article
- Keywords:
Desflurane;
Cardiac troponin I;
Myocardial enzyme;
Thoracic cancer
- From:
Cancer Research and Clinic
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of desflurane on cardiac troponin I (cTnI) and myocardial enzyme. Methods Thirty ASA Ⅰ~Ⅱpatients scheduled for selective operation were randomly divided into three groups of tenin each: Desflurane group(D group), Isoflurane group(I group) and Enflurane group(E group). Anesthesia was maintained with inhalation of 1.0MAC of desflurane, isoflurane, and enflurane in each group respectively. Blood samples were taken before anesthesia, 1 h after inhalation and at the end of inhalation for the determination of plasma cTnI, CK, CK-MB, AST and LDH activities. Results cTnI, AST, LDH, CK and CK-MB levels were normal before anesthesia. At the end of inhalation, CK increased significantly in three groups, CK-MB increased markedly in Enflurane group and Isoflurane group, but CK-MB level was normal in desflurane group. However, the CK-MB level was normal in all patients. cTnI, AST, LDH showed little changes during inhalation. Conclusions Inhalation of 1.0 MAC of desflurane, isoflurane and enflurane doesn't result in myocardial injury.
