Changes of expression of PECAM-1,P-selectin in activated platelet in patients with acute cerebral infarction
- VernacularTitle:急性脑梗死患者活化血小板表达血小板内皮细胞黏附分子-1、P-选择素的动态变化
- Author:
Haiying ZHU
;
Zhenpu LENG
;
Zaiying PANG
;
Xiao MAN
;
Yabo FENG
;
Zhaokong LIU
- Publication Type:Journal Article
- Keywords:
Brain infarction;
Platelet activation;
Antigens,CD31;
P-selectin
- From:
Chinese Journal of Neurology
2005;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes of expression of platelet PECAM-1,P-selectin in patients with acute cerebral infarction.Methods The platelet expression levels of PECAM-1,P-selectin in 35 patients with acute cerebral infarction were serially measured with whole blood flow cytometry 24,48 hours and 5,7,14 days after the onset,and were compared with those of 30 normal controls.Results The platelet expression levels of PECAM-1 and P-selectin in patients with cerebral infarction 24 hours after the onset(78.35?10.48,7.75?3.04 respectively)were higher than those of controls(48.89?10.84,2.18?0.83 respectively,all P
