Experimental study on ischemic injury of certical spinal cord after acute artery block
- VernacularTitle:动脉阻断致颈髓急性缺血性损伤的实验研究
- Author:
Qizhi SUN
;
Xianjun REN
;
Hongwei HU
- Publication Type:Journal Article
- Keywords:
anterior radicular artery;
anterior cervical spinal cord artery;
cervical spinal cord;
block of blood circulation;
Ischemia
- From:
Orthopedic Journal of China
2006;0(20):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To study the effect on ischemic injury of cervical spinal cord(CSC) by comparison on two different blocks of arteries supplying CSC.[Method]Forty-eight rabbits were divided into two groups: Group A,ligation and section of anterior cervical spinal cord artery(ASCA);group B ligation and section of both ACSCA and bilateral vertebral arteries before its entramce the foraman(indirect block of Anterior cervical radicular artery(ACRA).Bdood flow changes of CSC were meansured after 6 h,24 h and 72 h(each N=6) and muscle motor cooked potential(MMEP),local energy metabolism,and cell morplotogical changes of CSC were observed.[Result]In group A,blood flow of CSC was going down markedly and showed 50.2% decrease,but got partial recovery at 24 h and 72 h.Delitescence of MMEP prolongcd,ATP and EC descended profressivtly,showing an ischemic changes,In group B there showed greate,changes about every observation thay that in group A with significant difference at every time poinl between two groups(P
