Expression of estrogen receptor,VEGF and bFGF in infantile hemangioma
- VernacularTitle:雌激素受体、血管内皮生长因子和碱性成纤维细胞生长因子在小儿血管瘤中的表达及意义
- Author:
Chenghong JIANG
;
Fulian ZHUANG
;
Dongpo XU
;
Barui HUANG
;
Zhihui GUO
;
Biao WANG
- Publication Type:Journal Article
- Keywords:
Hemangioma;
Receptor,estrogen;
VEGF;
bFGF;
Immunohistochemistry reaction
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the function of estrogen in the proliferative and involuting stages of infantile hemangioma. Meothods Expression of estrogen receptor(ER),VEGF and bFGF were detected with SP immunohistochemical method in 42 cases of hemangiomas and 17 cases of vascular malformations.Results The label index(LI) of ER,VEGF and bFGF in the hemangioma was significantly higher than those in the vascular malformation and normal skin(P