A neuropsychological study of Alzheimer disease and mild cognitive impairment
- VernacularTitle:阿尔茨海默病和轻度认知功能障碍的神经心理学研究
- Author:
Ping GAO
;
Xiaojie CAI
;
Shaosen QIN
- Publication Type:Journal Article
- Keywords:
Alzheimer disease;
Cognition disorders;
Neuropsychological tests
- From:
Chinese Journal of Geriatrics
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the neuropsychological features of patients with Alzheimer disease (AD) and mild cognitive impairment (MCI). Methods Fifty-two AD, 26 MCI and 24 healthy aging cases were investigated by the clinical evaluation and a series of neuropsychological tests which include mini-mental state examination (MMSE), clinical dementia rating scale (CDR), activity of daily living scale (ADL) and clinical memory scale (CMS). Results The scores of the neuropsychological tests in AD,MCI and normal control groups were as follows: MMSE scores were 18. 9?5. 1, 26. 9?2. 1, 29. 0?1.1 respectively; ADL scores were 48. 3?17. 7, 26. 7?9. 3, 22. 1?4.1 respectively; Memory Quotient(MQ)scores were 52. 5?26. 7, 81. 3?10. 8, 101. 8?11. 6; CMS scores were 52. 5?26. 7, 81. 3?10. 8, 101. 8?11. 6 respectively. All neuropsychological tests except ADL in MCI group were significantly lower than those in the normal controKall P