Expression of protein kinase C-? and telomerase in human ameloblastoma
- VernacularTitle:人成釉细胞瘤中蛋白激酶C-?表达与端粒酶活性的关系
- Author:
Ming ZHONG
;
Luzhuang ZHANG
;
Bo ZHANG
- Publication Type:Journal Article
- Keywords:
Ameloblastoma;
Telomere;
Telomerase;
Protein kinase C-?
- From:
Journal of Practical Stomatology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the expression of protein kinase C-?(PKC-?)in human ameloblastoma(AB)and its relationship with human telomerase reverse transcriptase(hTERT).Methods:The expression of hTERT mRNA was detected by in situ hybridization and PKC-? protein by immunohistochemistry in 54 cases of AB,7 cases of normal oral mucosa(NOM)and 16 cases of odontogenic keratocyst(OKC).Results:The positive rate of hTERT mRNA in AB,OKC and NOM was 94.4%(51/54),87.5%(14/16)and 14.3%(1/7)(P
