Relationship between C-reaction protein (CRP) and glucose metabolism in advanced solid tumor patients
- VernacularTitle:晚期实体瘤患者C反应蛋白与糖代谢的关系
- Author:
Feng PAN
;
Ruiyan HUANG
;
Yanhong BAO
;
Jianguang ZHU
- Publication Type:Journal Article
- Keywords:
C-reaction protein;
Glucose metabolism;
Solid tumor
- From:
Cancer Research and Clinic
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between CRP and glucose metabolism in advanced solid tumor patients. Methods 32 advanced stage malignant tumor patients with mild pain took celecoxib 200mg/qd orally, the plasma level of CRP, FBS, FINS, IR were measured before taking drug and 5 days later. Results CRP is well related with FINS, IR, P level, CRP[(8.17?1.76) mg/L vs (4.37?0.65) mg/L], P(876?123)pmol/L vs (621?145) pmol/L], FINS[(14.23?7.21) ?U/L vs (9.83?3.37) ?U/L] and IR [(3.2?1.01) vs (1.9?0.78)] all were improved significantly after taking celecoxib. Conclusion CRP has some relationship with abnormal glucose metabolism in advanced stage malignant tumor patients, taking celecoxib may improve this abnormal glucose metabolism.
