The follow-up research on the relationship between hyperhomocysteinemia and the recurrence rate of cerebral infarction after previous stroke
- VernacularTitle:高同型半胱氨酸血症与脑梗死复发率关系的随访研究
- Author:
Xiaomu TAN
;
Jianguo LIU
;
Huaixiang LIU
;
Haifeng GAO
;
Zhecheng ZHANG
- Publication Type:Journal Article
- Keywords:
Hyperhomocysteinemia;
Brain infarction;
Recurrence;
Follow-up studies
- From:
Chinese Journal of Neurology
2005;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the possible effect of the plasma homocysteine level on the risk of recurrent cerebral infarction patients by follow-up research in hope for finding a new theoretical evidence for the therapy and the prophylaxis of cerebral infarction.Methods We determined the free plasma total homocysteine(tHcy)of 151 patients with acute cerebral infarction and 52 age-and gender-matched healthy controls by high-performance liquid chromatography,then we divided the patients into hyperhomocysteinemia (Hhcy)group and no hyperhomocysteinemia(Nhhcy)group according to the outcome.Within a 5-years follow-up period,we observed the recurrence of cerebral infarction in the 2 groups.Results There was no statistical deference in common information between Hhcy and Nhhcy group.But the recurrence rate of the Hhcy group,being 44.26%,was significantly higher than 12.22%of Nhhcy group(P
