Effect of L-dopa on plasma homocysteine in elderly patients with Parkinson's disease
- VernacularTitle:帕金森病患者左旋多巴治疗对血浆同型半胱氨酸的影响
- Author:
Hongmei WANG
;
Xuhua GE
;
Liansheng ZHOU
;
Deqin GENG
- Publication Type:Journal Article
- Keywords:
Parkinson disease;
Levodopa;
Homocysteine;
Vitamin B12;
Folic acid
- From:
Chinese Journal of Neurology
2005;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of L-dopa on plasma homocysteine and folic acid in patients with parkinsons' s disease(PD).Methods Twenty eight elderly PD patients and thirty normal subjects were enrolled in this group.The homocysteine,cobalamin and folate were examined in normal group and in PD group before treatment and after being treated with L-dopa for six moths respectively.Then the homocysteine,cobalamin and folate were compared between the two groups.Results The plasma homocysteine levels increased in PD patient group after being treated with L-dopa for six months(19.19? 8.01)?mol/L as compared with those of the PD group before treatment(12.50?3.78)?mol/L and those of control group(12.60?3.94)?mol/L(P
