Effect of electroacupuncture applied at acupoint on cognitive function in lithium-pilocarpine induced spontaneous recurrent epileptic rat
- VernacularTitle:电针穴位刺激对锂-匹罗卡品诱导性致痫大鼠认知功能的影响
- Author:
Jincun WANG
;
Weidong WANG
;
Xuedong LIU
;
Feng XIA
;
Xiaoni WEN
;
Yuangui HUANG
- Publication Type:Journal Article
- Keywords:
electroacupuncture;
acupoint;
cognitive function;
epilepsy;
lithium-pilocarpine
- From:Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of electroacupuncture applied at Baihui acupoint on cognitive function in lithium-pilocarpine induced spontaneous recurrent epileptic rat and provide some theoretical basis for acupoint stimulation treatment seizure.Methods Male mature Sprague Dawley rats were subjected to spontaneous recurrent epileptic model induced by lithium-pilocarpine,and divided into different groups randomly: acupoint group(electroacupuncture applied at Baihui acupoint),non-acupoint group(electroacupuncture located in close vicinity to the Baihui acupoint),and epileptic control group.Normal rats were subjected into normal control group.The Morris water maze test and step though test were carried out respectively to explore the effect of electroacupuncture applied at Baihui acupoint on the rats' learning and memory capacities.Results Compared with control group,acupoint rats in Morris water maze test time of finding the platform under the water surface decreased(P
