Proton magnetic resonance spectroscopy imaging study on prefrontal cortex in first fit schizophrenia
- VernacularTitle:首发精神分裂症患者前额叶磁共振质子波谱的成像
- Author:
Xiancang MA
- Publication Type:Journal Article
- Keywords:
schizophrenia;
prefrontal;
magnetic resonance spectroscopy
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To measure N-acetylaspartate(NAA),choline(CHO) and creatine(Cr) in prefrontal cortex of patients with schizophrenia using in vivo proton magnetic resonance spectroscopy imaging(H'MRSI).Methods H'MRSI was performed on the right and left prefrontal cortex in 20 patients with schizophrenia and 20 normals.The ratio of NAA/Cr to Cho/Cr was determined.Results The NAA/Cr ratio in patients was significant lower than that in normal controls.The CHO/Cr ratio had no significant difference between both groups.Conclusion The neuron function in prefrontal cortex might decrease in first fit schizophrenia.
