An analysis of the short-term effects with transbronchial arterial chemoembolization on intermediate or advanced lung cancer
- VernacularTitle:支气管动脉化疗栓塞治疗中晚期肺癌近期疗效探讨
- Author:
Liwei GAO
;
Zhirun LI
;
Yaolong YU
- Publication Type:Journal Article
- Keywords:
Transbronchial arterial chemoembolization;
Lung cancer
- From:
Cancer Research and Clinic
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the short-term treatment effects and adverse effect on intermediate or advanced lung cancer by means of transbronchial arterial chemoembolization. Methods 68 patients were included in this study. First bronchial arteriography was performed to identify the tumor-feeding branch, and super-catheterize it. After CBP, EPI and 5-Fu was infused, embolization with gelatin sponge was carried out, chemoembolization was reperformed at 4~6 weeks intervals, 136 times of chemoembolization were done in 68 cases. Results The tumor blush of 51 patients stained obviously ,the feeding arteries with the second treatment decreased obviously. In 68 patients, the overall response rate was 82.3 %, the clinical beneficial rate was 97.0 %. The main side effect was myelosuppression, especially granulocytopenia, which was similar to that of conventional intravenous chemotherapy. No other severe adverse effect was seen. Conclusions Transbronchial arterial chemoembolization by selective tumor-feeding arteries catheterization has good short-term effect and clinic beneficial rate in the treatment of intermediate or advanced lung cancer, but the long-term treatment effects will be studied in the future.
