Insulin up-regulates expression of apelin gene in 3T3-L1 cells:a preliminary observation
- VernacularTitle:胰岛素上调3T3-L1细胞apelin基因表达的初步观察
- Author:
Li WEI
;
Xinghua HOU
;
Weiping JIA
- Publication Type:Journal Article
- Keywords:
Apelin;
Adipocytes;
3T3-L1 cell;
Insulin
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Expression of apelin mRNA in the isolated mouse adipocytes was confirmed by Northern blot. The level of apelin mRNA increased during stage of differentiation of 3T3-L1 cells. Insulin up-regulated the apelin expression in 3T3-L1 adipocytes, suggesting that apelin expression in adipocyte may correlate with obesity, insulin resistance and hypertension.
